Brucella & Diagnostics Section background

Brucella & Diagnostics Section

The Brucella & Diagnostics Section is engaged in the production of Brucella vaccines and the development of diagnostic reagents for identifying bacterial and zoonotic diseases in livestock. The section plays a key role in controlling brucellosis and supporting national animal health surveillance programs.

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Overview

The Brucella & Diagnostics Section focuses on the production of vaccines and diagnostic reagents for the detection and prevention of Brucellosis — a zoonotic disease affecting cattle, goats, and humans. The section operates under biosafety level-3 (BSL-3) containment to ensure safe handling of pathogenic organisms.

The division also develops and supplies high-quality diagnostic kits, including antigens and test reagents used for serological screening of animal diseases.

Major Vaccines and Diagnostics Produced
  • Brucella Abortus S19 Vaccine — Live vaccine for immunizing female calves against bovine brucellosis.
  • Brucella Abortus RB51 Vaccine — Smooth strain vaccine designed for safer use in adult cattle.
  • Rose Bengal Plate Test (RBPT) Antigen — Used for rapid detection of brucellosis in field conditions.
  • Brucella Standard Agglutination Test (SAT) Antigen — Quantitative serological test reagent for confirmatory diagnosis.
Infrastructure and Facilities

The section operates under advanced biosafety infrastructure featuring:

  • • BSL-3 compliant laboratory for Brucella culture and vaccine preparation
  • • Dedicated diagnostic production suites with clean air systems
  • • Automated antigen blending and vial filling units
  • • Cold storage facilities for antigen preservation
  • • Fully equipped serology and microbiology diagnostic units
Research and Development

The R&D team continuously works on improving vaccine safety profiles, antigenic stability, and developing advanced diagnostic assays such as ELISA and lateral flow kits. Collaborations with national reference laboratories enhance validation and field-level performance studies.

Quality Assurance

Every vaccine and diagnostic reagent is subjected to safety, sterility, and potency tests as per national veterinary biological standards. The section operates under strict QA-QC supervision, ensuring reliability and traceability of each batch.