Anthrax Spore Vaccine Facility background

Anthrax Spore Vaccine Facility

The Anthrax Spore Vaccine Facility is a specialized production unit dedicated to manufacturing the live spore vaccine for the prevention of anthrax in livestock. Operating under high biosafety standards, the facility ensures consistent production of potent and safe vaccines critical for controlling anthrax outbreaks in endemic regions.

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Overview

The Anthrax Spore Vaccine Facility specializes in the large-scale production of the Anthrax Spore Vaccine used to immunize cattle, sheep, and goats against anthrax. The vaccine is based on the Sterne strain (34F2) of Bacillus anthracis, known for its safety and effectiveness.

All stages of production, from seed culture to lyophilization and final packaging, are conducted under aseptic and controlled environmental conditions in compliance with national veterinary biological standards.

Vaccine Specifications
  • Type: Live spore vaccine (Sterne strain 34F2)
  • Dosage: 1 ml for cattle and buffaloes; 0.5 ml for sheep and goats
  • Route: Subcutaneous injection
  • Shelf Life: 12 months (when stored at 2–8°C)
  • Presentation: 50-dose and 100-dose vials
Infrastructure and Facilities

The facility is equipped with high-level biosafety infrastructure including:

  • • BSL-III compliant laboratory for spore culture handling
  • • Sterile production suites with HEPA filtration systems
  • • Automated filling and sealing lines
  • • Freeze-drying (lyophilization) systems for vaccine stabilization
  • • Dedicated quality control laboratory for microbiological and potency assays
Research and Development

The facility continuously works on enhancing vaccine stability, improving production yield, and exploring recombinant antigen-based anthrax vaccine formulations. Collaboration with national biosafety and veterinary research centers supports ongoing innovation.

Quality Assurance

Every batch of vaccine is tested for viability, purity, and safety as per the Indian Veterinary Biological Standards. Quality audits and process validations ensure the product meets regulatory and international standards.