Small Animal Testing with BSL-III Facility
The Small Animal Testing Facility (BSL-III) is a specialized high-containment unit designed for conducting in-vivo testing of vaccines, antigens, and biological samples under stringent biosafety conditions. It enables the evaluation of product safety, potency, and efficacy in compliance with national veterinary biological standards.
Overview
The Small Animal Testing with BSL-III Facility provides a controlled environment for animal challenge studies, vaccine potency testing, and biosafety evaluations. It supports the validation of vaccines and diagnostic reagents before regulatory approval and field release.
The facility adheres to OIE, CPCSEA, and NABL guidelines, ensuring humane handling, ethical testing practices, and complete containment of infectious materials.
Core Functions
- • In-vivo safety and potency testing of bacterial and viral vaccines
- • Challenge trials using standard reference strains
- • Evaluation of vaccine efficacy under controlled biosafety conditions
- • Toxicity and sterility studies prior to product release
- • Support for diagnostic reagent validation and research studies
Infrastructure and Facilities
The BSL-III facility is equipped with advanced containment and monitoring systems designed to ensure complete biosecurity and staff safety.
- • BSL-III compliant animal rooms with controlled air pressure differentials
- • HEPA-filtered air supply and exhaust systems
- • Double-door autoclaves and pass-through chambers
- • Animal holding and challenge chambers with biosafety isolators
- • Effluent decontamination and bio-waste treatment units
Quality and Regulatory Compliance
All experimental activities are conducted under approved protocols, following CPCSEA animal ethics guidelines. The facility undergoes regular biosafety audits and quality inspections to ensure continued accreditation and operational excellence.
Research and Collaboration
The facility collaborates with R&D, QA, and vaccine production units to generate scientific data supporting product licensing and efficacy demonstration. It also partners with national research institutes for high-containment studies involving emerging zoonotic pathogens.
Commitment to Biosafety and Ethics
The Small Animal Testing Facility operates with an uncompromising commitment to biosafety, animal welfare, and data integrity — ensuring every product released for field use is safe, potent, and reliable.